Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 9/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 6/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10513011 | 0.83 | OGA (0.36) | SSTR4SSTR1OGADPP4DPP8 | |
| SCHEMBL10513014 | 0.83 | OGA (0.36) | SSTR4SSTR1OGADPP4DPP8 | |
| SCHEMBL24928079 | 0.83 | OGA (0.36) | SSTR4SSTR1OGADPP4DPP8 | |
| SCHEMBL26620621 | 0.80 | SSTR4 (0.48) | SSTR4SSTR1 | |
| SCHEMBL15980408 | 0.80 | OGA (0.38) | SSTR4SSTR1OGACA1CA2 | |
| SCHEMBL31643024 | 0.79 | DPP4 (0.37) | SSTR4SSTR1CA1CA2DPP4 | |
| SCHEMBL19658458 | 0.78 | DPP4 (0.36) | CA1CA2DPP4DPP8CA12 | |
| SCHEMBL19658499 | 0.78 | DPP4 (0.36) | CA1CA2DPP4DPP8CA12 | |
| SCHEMBL28826192 | 0.78 | SSTR4 (0.47) | SSTR4SSTR1CA1CA2 | |
| SCHEMBL26620624 | 0.76 | SSTR4 (0.36) | SSTR4SSTR1OGACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019215341-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-11-14 | — | — | WO | disclosed |