Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 10/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 6/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18909588 | 0.88 | CTSK (0.45) | SSTR4SSTR1CTSKCA1CA2 | |
| SCHEMBL31368050 | 0.86 | CTSK (0.41) | SSTR4SSTR1CTSKCA1CA2 | |
| SCHEMBL24928078 | 0.86 | CTSK (0.41) | SSTR4SSTR1CTSKCA1CA2 | |
| SCHEMBL24928082 | 0.86 | CTSK (0.41) | SSTR4SSTR1CTSKCA1CA2 | |
| SCHEMBL19465291 | 0.84 | CTSK (0.46) | SSTR4SSTR1CTSKCA1CA2 | |
| SCHEMBL24854857 | 0.84 | CTSK (0.46) | SSTR4SSTR1CTSKCA1CA2 | |
| SCHEMBL20070141 | 0.84 | CTSK (0.46) | SSTR4SSTR1CTSKCA1CA2 | |
| SCHEMBL16058570 | 0.83 | CTSK (0.43) | CTSKCA1CA2NFKB1NFKB2 | |
| SCHEMBL16058571 | 0.83 | CTSK (0.43) | CTSKCA1CA2NFKB1NFKB2 | |
| SCHEMBL31634070 | 0.83 | USP30 (0.47) | CTSKCA1CA2CYP2C9HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235389-A1 | P53 MODULATORS | NESTED THERAPEUTICS, INC. (US) | 2025-11-13 | — | — | WO | disclosed |
| WO-2024215802-A1 | BENZOFURANYL AND BENZOTHIENYL COMPOUNDS AS P53 MODULATORS | NESTED THERAPEUTICS, INC. (US) | 2024-10-17 | — | — | WO | disclosed |
| CN-115003299-A | Methods and compounds for restoring function of mutant p53 | 皮姆维制药公司 | 2022-09-02 | — | — | CN | disclosed |