SCHEMBL21564681

SCHEMBL21564681

Clc1cc(Cl)cc(-c2cc(CN3CCCOCC3)cc(Oc3cnc(N4CCNCC4)nc3)n2)c1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23375890 0.92 FURIN (0.74) FURIN
SCHEMBL21564420 0.90 FURIN (0.69) FURIN
SCHEMBL29198886 0.88 FURIN (0.73) FURIN
SCHEMBL24872410 0.86 FURIN (0.74) FURIN
SCHEMBL27032447 0.85 FURIN (0.78) FURIN
SCHEMBL21555627 0.85 FURIN (0.75) FURIN
SCHEMBL21555628 0.85 FURIN (0.75) FURIN
SCHEMBL21564510 0.83 FURIN (0.58) FURIN
SCHEMBL21551259 0.82 FURIN (0.68) FURIN
SCHEMBL21551189 0.82 FURIN (0.81) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 — — EP disclosed
WO-2019215341-A1 FURIN INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-11-14 — — WO disclosed
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