SCHEMBL21564707

SCHEMBL21564707

COC(=O)CCN1CCN(c2ncc(Oc3cc(CN4CCC5CC5CC4)cc(-c4cc(Cl)cc(Cl)c4)n3)cn2)CC1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21564704 0.92 FURIN (0.78) FURIN
SCHEMBL21551522 0.90 FURIN (0.71) FURIN
SCHEMBL21551520 0.90 FURIN (0.71) FURIN
SCHEMBL21551521 0.90 FURIN (0.71) FURIN
SCHEMBL29928219 0.89 FURIN (0.88) FURIN
SCHEMBL21551225 0.89 FURIN (0.88) FURIN
SCHEMBL30792571 0.89 FURIN (0.78) FURIN
SCHEMBL21551658 0.89 FURIN (0.76) FURIN
SCHEMBL21551294 0.88 FURIN (0.87) FURIN
SCHEMBL21551308 0.88 FURIN (0.64) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 — — EP disclosed
WO-2019215341-A1 FURIN INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-11-14 — — WO disclosed
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