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SCHEMBL21565261

SCHEMBL21565261

CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCC(C=O)NC(=O)CCCCCCCCCCCCCCCCC=O

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.54
▸ LPAR1 Q92633 3/20 0.41
▸ LPAR2 Q9HBW0 2/20 0.41
▸ ENPP2 Q13822 1/20 0.41
▸ EPHX2 P34913 2/20 0.40
▸ SLC6A5 Q9Y345 2/20 0.39
▸ CNR1 P21554 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14748066 0.94 GLP1R (0.60) GLP1RLPAR1LPAR2ENPP2EPHX2
SCHEMBL25746490 0.92 GLP1R (0.45) GLP1RLPAR1LPAR2ENPP2EPHX2
SCHEMBL12296713 0.91 GLP1R (0.59) GLP1REPHX2SLC6A5CNR1KDM4E
SCHEMBL12295313 0.91 GLP1R (0.59) GLP1REPHX2SLC6A5CNR1KDM4E
SCHEMBL12295886 0.91 GLP1R (0.59) GLP1REPHX2SLC6A5CNR1KDM4E
SCHEMBL12296113 0.90 GLP1R (0.58) GLP1REPHX2CNR1KDM4E
SCHEMBL23977334 0.87 GLP1R (0.70) GLP1REPHX2SLC6A5
SCHEMBL18552234 0.87 GLP1R (0.70) GLP1REPHX2SLC6A5
SCHEMBL12295261 0.85 GLP1R (0.69) GLP1REPHX2
SCHEMBL12296101 0.85 GLP1R (0.69) GLP1REPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019215063-A1 SOLID COMPOSITIONS COMPRISING A GLP-1 AGONIST AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID NOVO NORDISK A/S (DK) 2019-11-14 — — WO disclosed