SCHEMBL25746490

SCHEMBL25746490

CC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCC(C=O)NC(=O)CCCCCCCCCCCCCCCCC=O

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.45
LPAR2 Q9HBW0 3/20 0.34
LPAR1 Q92633 2/20 0.34
ENPP2 Q13822 1/20 0.34
CNR1 P21554 2/20 0.31
EPHX2 P34913 2/20 0.31
GLO1 Q04760 1/20 0.30
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21565261 0.92 GLP1R (0.54) GLP1RLPAR2LPAR1ENPP2CNR1
SCHEMBL23031081 0.91 GLP1R (0.50) GLP1RCNR1EPHX2FAAH
SCHEMBL22619268 0.87 GLP1R (0.51) GLP1RLPAR2LPAR1ENPP2GLO1
SCHEMBL27257542 0.87 GLP1R (0.39) GLP1R
SCHEMBL14748066 0.85 GLP1R (0.60) GLP1RLPAR2LPAR1ENPP2EPHX2
SCHEMBL12295886 0.82 GLP1R (0.59) GLP1RCNR1EPHX2FAAH
SCHEMBL12296713 0.82 GLP1R (0.59) GLP1RCNR1EPHX2FAAH
SCHEMBL24822980 0.82 GLP1R (0.48) GLP1REPHX2GLO1
SCHEMBL12295313 0.82 GLP1R (0.59) GLP1RCNR1EPHX2FAAH
SCHEMBL23660032 0.82 GLP1R (0.48) GLP1RLPAR2LPAR1ENPP2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110758-A1 EFFECTIVE DOSES OF CNP CONJUGATES ASCENDIS PHARMA GROWTH DISORDERS A/S (DK) 2023-06-22 WO disclosed