Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21552609 | 0.82 | OTUD7B (0.32) | OTUD7BIRAK4 | |
| SCHEMBL16187705 | 0.77 | BRD4 (0.36) | OTUD7BALDH1A1L3MBTL1IRAK4 | |
| SCHEMBL22701749 | 0.74 | IRAK4 (0.33) | ALDH1A1L3MBTL1IRAK4KDM4EMEN1 | |
| SCHEMBL14885496 | 0.69 | CREBBP (0.36) | OTUD7BIRAK4 | |
| SCHEMBL17136992 | 0.69 | CREBBP (0.36) | OTUD7BIRAK4 | |
| SCHEMBL24851237 | 0.69 | — | — | |
| SCHEMBL21552636 | 0.69 | CRBN (0.32) | OTUD7B | |
| SCHEMBL21552583 | 0.69 | CRBN (0.32) | OTUD7B | |
| SCHEMBL21565341 | 0.69 | CRBN (0.32) | OTUD7B | |
| SCHEMBL20607979 | 0.66 | CRBN (0.42) | OTUD7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217890-A1 | NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2019-11-14 | — | — | WO | disclosed |