SCHEMBL21565728

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21565624	0.88	HRH3 (0.53)	ALDH1A1SLC16A3HRH3OPRM1OPRK1
	SCHEMBL21565500	0.88	CHKA (0.54)	SLC16A3HRH3HRH4CHKA
	SCHEMBL30229943	0.88	CHKA (0.54)	SLC16A3HRH3HRH4CHKA
	SCHEMBL21565727	0.87	HRH3 (0.56)	ALDH1A1HRH3HRH4CNR2CYP2C19
	SCHEMBL21565653	0.85	ALDH1A1 (0.47)	ALDH1A1GAASLC16A3MEN1KMT2A
	SCHEMBL21565602	0.85	HRH3 (0.43)	SLC16A3HRH3HRH4CHKA
	SCHEMBL21565737	0.84	CHKA (0.60)	SLC16A3HRH3CHKA
	SCHEMBL21565515	0.83	HRH3 (0.48)	SLC16A3HRH3HRH4
	SCHEMBL21565527	0.82	HRH3 (0.57)	MEN1KMT2AHRH3HRH4CNR2
	SCHEMBL21565734	0.82	CXCR4 (0.48)	ROCK2ROCK1MEN1KMT2AHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.