Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 12/20 | 1.00 |
| ▸ | CES1 | P23141 | 12/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | DAO | P14920 | 1/20 | 0.65 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzil SCHEMBL7142843 | 1.00 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL66 | 1.00 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL28475956 | 1.00 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL9517636 | 1.00 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL9799726 | 0.97 | CES2 (0.93) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL4957522 | 0.97 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL16390243 | 0.97 | CES2 (0.93) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL1002038 | 0.97 | CES2 (0.93) | CES2CES1TSHRDAONAPRT | |
| SCHEMBL1195835 | 0.97 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL10556962 | 0.97 | CES2 (0.93) | CES2CES1TSHRDAONAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240084950-A1 | FORMALDEHYDE FREE COMPOSITES MADE WITH CARBOHYDRATE AND ALPHA-CARBON NUCLEOPHILE BINDER COMPOSITIONS | JOHNS MANVILLE | 2024-03-14 | — | — | US | disclosed |
| US-11841106-B2 | Formaldehyde free composites made with carbohydrate and alpha-carbon nucleophile binder compositions | JOHNS MANVILLE (US) | 2023-12-12 | — | — | US | disclosed |
| CN-114895535-B | Super-resolution lithography method based on double-step absorption effect and STED principle | 之江实验室 | 2022-12-02 | — | — | CN | disclosed |
| CN-114895535-A | Super-resolution lithography method based on double-step absorption effect and STED principle | 之江实验室 | 2022-08-12 | — | — | CN | disclosed |
| US-20200056327-A1 | Binder-consolidated textile fabric, method for its manufacture and its use | JOHNS MANVILLE | 2020-02-20 | — | — | US | disclosed |
| US-20160312941-A1 | FORMALDEHYDE FREE COMPOSITES MADE WITH CARBOHYDRATE AND ALPHA-CARBON NUCLEOPHILE BINDER COMPOSITIONS | JOHNS MANVILLE | 2016-10-27 | — | — | US | disclosed |
| US-7973034-B2 | Ameliorating toxic effects of such as cancer therapy drugs or addictive drug overdose | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2011-07-05 | — | — | US | disclosed |
| US-20080146548-A1 | AMIDE, ARYL SULFONAMIDE, ARYL UREA, AND a,b-DIKETONE DERIVED CARBOXYLESTERASE INHIBITORS, AND THEIR METHODS OF USE | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2008-06-19 | — | — | US | disclosed |
| US-20050054691-A1 | Carboxylesterase inhibitors | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2005-03-10 | — | — | US | disclosed |
| US-4369207-A | PHOTOPOLYMERIZING | TEIJIN LIMITED (JP) | 1983-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054691-A1 | Carboxylesterase inhibitors | CES1, CES2, BCHE | CES2 2/4885CES1 1/4885TSHR 4332/4885 |
| US-20080146548-A1 | AMIDE, ARYL SULFONAMIDE, ARYL UREA, AND a,b-DIKETONE DERIVED CARBOXYLESTERASE INHIBITORS, AND THEIR METHODS OF USE | CES1, BCHE, CES2 | CES2 3/4885CES1 1/4885TSHR 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.