SCHEMBL2156598

SCHEMBL2156598

NCC(N)C(CCO)CCO

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1408758 0.74
SCHEMBL3634009 0.72
SCHEMBL16111959 0.71 METAP1 (0.41) ALDH1A1
SCHEMBL3671438 0.71 THRB (0.36) ALDH1A1TSHRTHRB
SCHEMBL5052093 0.71 THRB (0.36) THRB
SCHEMBL118331 0.70
SCHEMBL12191383 0.69 THRB (0.44) TSHRTHRB
SCHEMBL42985 0.69
SCHEMBL7777186 0.69
SCHEMBL14872061 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1603846-B1 STRENGTH IMPROVEMENT ADMIXTURE CONSTR RES & TECH GMBH (DE) 2012-07-11 EP claimed
EP-1603846-A2 STRENGTH IMPROVEMENT ADMIXTURE Construction Research & Technology GmbH (DE) 2005-12-14 EP claimed
US-20050188896-A1 Amine containing strength improvement admixture CONSTRUCTION RESEARCH & TECHNOLOGY GMBH 2005-09-01 US claimed
US-20040198873-A1 Strength improvement admixture CONSTRUCTION RESEARCH AND TECHNOLOGY GMBH 2004-10-07 US claimed
WO-2004076376-A2 STRENGTH IMPROVEMENT ADMIXTURE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2004-09-10 WO claimed
US-8258210-B2 Increasing compressive strength of cements without increasing setting time and polycarboxylic groups as dispersants CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2012-09-04 US disclosed
EP-1603846-B1 STRENGTH IMPROVEMENT ADMIXTURE CONSTR RES & TECH GMBH (DE) 2012-07-11 EP disclosed
US-7972435-B2 Amine containing strength improvement admixture CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2011-07-05 US disclosed
US-20090292041-A1 AMINE CONTAINING STRENGTH IMPROVEMENT ADMIXTURE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2009-11-26 US disclosed
US-20040198873-A1 Strength improvement admixture CONSTRUCTION RESEARCH AND TECHNOLOGY GMBH 2004-10-07 US disclosed