Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 4/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568161 | 0.93 | KDM4E (0.57) | KDM4ERECQLDYRK1AFSCN1HSD17B10 | |
| SCHEMBL21569108 | 0.90 | KDM4E (0.56) | KDM4ERECQLDYRK1AFSCN1HSD17B10 | |
| SCHEMBL21568084 | 0.89 | HSD17B10 (0.60) | KDM4ERECQLDYRK1AFSCN1BLM | |
| SCHEMBL21568179 | 0.88 | KDM4E (0.53) | KDM4ERECQLDYRK1AFSCN1HSD17B10 | |
| SCHEMBL21568063 | 0.87 | HSD17B10 (0.57) | KDM4ERECQLDYRK1AFSCN1BLM | |
| SCHEMBL21568250 | 0.86 | BLM (0.55) | KDM4ERECQLDYRK1AFSCN1BLM | |
| SCHEMBL21568967 | 0.85 | BLM (0.54) | KDM4ERECQLDYRK1AFSCN1BLM | |
| SCHEMBL21568078 | 0.85 | HSD17B10 (0.57) | KDM4ERECQLDYRK1AFSCN1BLM | |
| SCHEMBL21568257 | 0.84 | KDM4E (0.61) | KDM4ERECQLDYRK1AFSCN1HSD17B10 | |
| SCHEMBL21568318 | 0.82 | DYRK1A (0.57) | KDM4EDYRK1AHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217509-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | HB THERAPEUTICS INC. (US) | 2019-11-14 | — | — | WO | disclosed |