Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23256895 | 0.89 | DYRK1A (0.68) | DYRK1ALMNAPOLBMAPTMEN1 | |
| SCHEMBL23256883 | 0.85 | DYRK1A (0.66) | DYRK1ALMNAPOLBMAPTMEN1 | |
| SCHEMBL23256871 | 0.84 | SMN1; SMN2 (0.66) | DYRK1AMAPTMEN1KMT2AGSK3B | |
| SCHEMBL21568073 | 0.84 | DYRK1A (0.62) | DYRK1ALMNAPOLBMAPTMEN1 | |
| SCHEMBL21568123 | 0.84 | DYRK1A (0.65) | DYRK1ALMNAPOLBMAPTMEN1 | |
| SCHEMBL26034949 | 0.84 | DYRK1A (0.61) | DYRK1ALMNAPOLBMAPTMEN1 | |
| SCHEMBL23256870 | 0.84 | DYRK1A (0.70) | DYRK1ALMNAPOLBMAPTMEN1 | |
| SCHEMBL21568127 | 0.83 | CSNK1D (0.72) | DYRK1ALMNAPOLBMAPTMEN1 | |
| SCHEMBL23256894 | 0.83 | DYRK1A (0.64) | DYRK1ALMNAPOLBMAPTMEN1 | |
| SCHEMBL21568318 | 0.82 | DYRK1A (0.57) | DYRK1ALMNAPOLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217509-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | HB THERAPEUTICS INC. (US) | 2019-11-14 | — | — | WO | disclosed |