Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568188 | 0.89 | DYRK1A (0.61) | DYRK1AHSD17B10CSNK1DHDAC6HDAC3 | |
| SCHEMBL21568734 | 0.87 | DYRK1A (0.59) | DYRK1AHSD17B10CSNK1DHDAC6HDAC3 | |
| SCHEMBL21568264 | 0.86 | DYRK1A (0.58) | DYRK1AHSD17B10CSNK1DHDAC6HDAC3 | |
| SCHEMBL21568094 | 0.86 | CSNK1D (0.58) | DYRK1AHSD17B10CSNK1DHDAC6HDAC3 | |
| SCHEMBL21568093 | 0.85 | DYRK1A (0.59) | DYRK1AHSD17B10CSNK1DHDAC6HDAC3 | |
| SCHEMBL21568172 | 0.81 | DYRK1A (0.60) | DYRK1AHSD17B10CSNK1DHDAC6HDAC3 | |
| SCHEMBL18154477 | 0.81 | DYRK1A (0.81) | DYRK1AHSD17B10CSNK1DHDAC6HDAC3 | |
| SCHEMBL21568287 | 0.80 | DYRK1A (0.61) | DYRK1AHSD17B10CSNK1DHDAC6HDAC3 | |
| SCHEMBL21569137 | 0.78 | DYRK1A (0.59) | DYRK1AHSD17B10CSNK1DHDAC6HDAC3 | |
| SCHEMBL21568284 | 0.78 | DYRK1A (0.59) | DYRK1AHSD17B10CSNK1DHDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217509-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | HB THERAPEUTICS INC. (US) | 2019-11-14 | — | — | WO | disclosed |