Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568666 | 1.00 | ADRB2 (0.59) | ADRB2CHRM3ADRB1ADRB3DRD2 | |
| SCHEMBL21568631 | 0.94 | ADRB2 (0.65) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568677 | 0.94 | ADRB2 (0.65) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568629 | 0.94 | ADRB2 (0.65) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568676 | 0.94 | ADRB2 (0.65) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL18897343 | 0.89 | ADRB2 (0.68) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568539 | 0.89 | ADRB2 (0.68) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568535 | 0.87 | ADRB2 (0.66) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568534 | 0.87 | ADRB2 (0.66) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL18259933 | 0.87 | ADRB2 (0.79) | ADRB2CHRM3ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303333-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2019-11-20 | — | — | EP | claimed |
| EP-3303333-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2019-11-20 | — | — | EP | disclosed |