⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29574637 | 0.77 | — | — | |
| SCHEMBL7664828 | 0.77 | — | — | |
| SCHEMBL29896206 | 0.77 | — | — | |
| SCHEMBL12193022 | 0.77 | — | — | |
| SCHEMBL8237147 | 0.77 | — | — | |
| SCHEMBL23530510 | 0.77 | — | — | |
| SCHEMBL2307410 | 0.77 | — | — | |
| SCHEMBL6982118 | 0.77 | — | — | |
| SCHEMBL1413453 | 0.77 | — | — | |
| SCHEMBL17911800 | 0.76 | TRPA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| EP-3569602-B1 | IMIDAZOPYRAZINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | DONGGUAN ZHENGXING BEITE MEDICINE TECH CO LTD (CN) | 2022-11-23 | — | — | EP | disclosed |
| US-10919899-B2 | Imidazopyrazine compounds, preparation methods and uses thereof | DONGGUAN ZHENXING-BEITE MEDICINE TECHNOLOGY CO., LTD. (CN) | 2021-02-16 | — | — | US | disclosed |
| CN-106749268-B | Heteroaromatic compounds and their use in medicine | 广东东阳光药业有限公司 | 2020-10-09 | — | — | CN | disclosed |
| EP-3569602-A1 | IMIDAZOPYRAZINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Dongguan Zhengxing-Beite Medicine Technology Co., Ltd. (CN) | 2019-11-20 | — | — | EP | disclosed |
| CN-106588937-B | Imidazopyrazines and its preparation method and application | 东莞市真兴贝特医药技术有限公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-106588937-A | Imidazopyrazine compound, and preparation method and application thereof | 东莞市真兴贝特医药技术有限公司 | 2017-04-26 | — | — | CN | disclosed |