Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.67 |
| ▸ | ERBB2 | P04626 | 17/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14855250 | 1.00 | EGFR (0.67) | EGFRERBB2 | |
| SCHEMBL15319836 | 0.95 | EGFR (0.67) | EGFRERBB2 | |
| SCHEMBL15319835 | 0.95 | EGFR (0.67) | EGFRERBB2 | |
| SCHEMBL15319830 | 0.95 | EGFR (0.67) | EGFRERBB2 | |
| SCHEMBL15319833 | 0.95 | EGFR (0.67) | EGFRERBB2 | |
| SCHEMBL14854867 | 0.93 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL14854883 | 0.93 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL14854869 | 0.93 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL14854879 | 0.93 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL14855102 | 0.93 | EGFR (0.78) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222620-B1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) | 2019-11-20 | — | — | EP | claimed |