Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23961880 | 0.81 | HDAC1 (0.34) | MEN1KMT2AHDAC1ALDH1A1EPHX2 | |
| SCHEMBL24591722 | 0.81 | MEN1 (0.38) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL19523435 | 0.80 | MCL1 (0.37) | MEN1KMT2ARAB9AEPHX2 | |
| SCHEMBL23929057 | 0.79 | ACP1 (0.38) | MEN1KMT2AALDH1A1EPHX2L3MBTL1 | |
| SCHEMBL21569775 | 0.78 | CA1 (0.36) | MEN1KMT2ACA1CA2EPHX2 | |
| SCHEMBL6889241 | 0.77 | MEN1 (0.62) | MEN1KMT2AALDH1A1EPHX2L3MBTL1 | |
| SCHEMBL15220896 | 0.76 | MCL1 (0.33) | KMT2AALDH1A1EPHX2 | |
| SCHEMBL27102318 | 0.75 | HDAC1 (0.32) | HDAC1ALDH1A1 | |
| SCHEMBL7531907 | 0.75 | MEN1 (0.38) | MEN1KMT2AHDAC1ALDH1A1CA1 | |
| SCHEMBL24591803 | 0.74 | MEN1 (0.36) | MEN1KMT2AHDAC1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217591-A1 | ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-11-14 | — | — | WO | disclosed |