SCHEMBL23929057

SCHEMBL23929057

O=C(CS(=O)(=O)O)NCCS(=O)(=O)O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 7/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
PTGS1 P23219 1/20 0.35
PDE4A P27815 1/20 0.35
LMNA P02545 1/20 0.35
SLC6A6 P31641 1/20 0.35
CYP2C19 P33261 1/20 0.35
BLM P54132 1/20 0.35
EPHX2 P34913 1/20 0.33
CYP2D6 P10635 1/20 0.32
APP P05067 1/20 0.32
CASP2 P42575 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4809620 0.81 ALDH1A1 (0.36) MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL4809608 0.81 ALDH1A1 (0.36) MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL30407466 0.81 L3MBTL1 (0.47) MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL6889241 0.79 MEN1 (0.62) MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL5840814 0.79 PTGS1 (0.44) MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL6140532 0.79 HDAC3 (0.38) ACP1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL1492162 0.79 LMNA (0.44) MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL21569786 0.79 MEN1 (0.35) ACP1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL24670606 0.78 PTGS1 (0.42) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL10002585 0.78 PTGS1 (0.36) PTGS1PDE4ALMNASLC6A6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210330792-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210330792-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS PPOX, PPIB, PPIA ACP1 2394/4885MEN1 3718/4885KMT2A 4216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.