Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.56 |
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | RRM1 | P23921 | 1/20 | 0.51 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463461 | 1.00 | DPP7 (0.56) | DPP7DPP4DPP9DPP8RRM1 | |
| SCHEMBL10474841 | 1.00 | DPP7 (0.56) | DPP7DPP4DPP9DPP8RRM1 | |
| SCHEMBL4164602 | 0.89 | DPP7 (0.67) | DPP7DPP4DPP9DPP8RRM1 | |
| SCHEMBL10046565 | 0.89 | DPP7 (0.67) | DPP7DPP4DPP9DPP8RRM1 | |
| SCHEMBL10162471 | 0.86 | GRM8 (0.56) | DPP7DPP4DPP9DPP8RRM1 | |
| SCHEMBL29372609 | 0.86 | GRM8 (0.56) | DPP7DPP4DPP9DPP8RRM1 | |
| SCHEMBL3038975 | 0.86 | DPP7 (0.73) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL11221465 | 0.86 | DPP7 (0.73) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL13493919 | 0.86 | DPP7 (0.73) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL11221462 | 0.86 | DPP7 (0.73) | DPP7RRM1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217591-A1 | ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-11-14 | — | — | WO | disclosed |