SCHEMBL463461

SCHEMBL463461

CCCNC(=O)C(N)CCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 2/20 0.56
▸ DPP4 P27487 2/20 0.51
▸ DPP9 Q86TI2 2/20 0.51
▸ DPP8 Q6V1X1 1/20 0.51
▸ RRM1 P23921 1/20 0.51
▸ GRM8 O00222 1/20 0.50
▸ GRM6 O15303 1/20 0.50
▸ GRIN2D O15399 1/20 0.50
▸ GRIN3B O60391 1/20 0.50
▸ GSR P00390 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ GRIK1 P39086 1/20 0.50
▸ GRM5 P41594 1/20 0.50
▸ GRIA1 P42261 1/20 0.50
▸ GRIA2 P42262 1/20 0.50
▸ GRIA3 P42263 1/20 0.50
▸ SLC1A3 P43003 1/20 0.50
▸ SLC1A2 P43004 1/20 0.50
▸ SLC1A1 P43005 1/20 0.50
▸ GRIA4 P48058 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21569893 1.00 DPP7 (0.56) DPP7DPP4DPP9DPP8RRM1
SCHEMBL10474841 1.00 DPP7 (0.56) DPP7DPP4DPP9DPP8RRM1
SCHEMBL4164602 0.89 DPP7 (0.67) DPP7DPP4DPP9DPP8RRM1
SCHEMBL10046565 0.89 DPP7 (0.67) DPP7DPP4DPP9DPP8RRM1
SCHEMBL10162471 0.86 GRM8 (0.56) DPP7DPP4DPP9DPP8RRM1
SCHEMBL29372609 0.86 GRM8 (0.56) DPP7DPP4DPP9DPP8RRM1
SCHEMBL3038975 0.86 DPP7 (0.73) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL11221465 0.86 DPP7 (0.73) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL13493919 0.86 DPP7 (0.73) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL11221462 0.86 DPP7 (0.73) DPP7RRM1GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120064148-A1 PH-RESPONSIVE LIPOSOME BIONANOSHEETER CO., LTD. (JP) 2012-03-15 — — US disclosed
US-7198958-B2 Method for increasing hydrophilicity of fluorescent label compounds ARCTIC DIAGNOSTICS OY (FI) 2007-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120064148-A1 PH-RESPONSIVE LIPOSOME LIPA, SMPD3, SMPD1 DPP7 3513/4885DPP4 4217/4885DPP9 4078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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