SCHEMBL21569933

CCCC1O[C@@H]2CC3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)COC(=O)NCCSC)O1

nearest known ligand 0.67

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	NR3C1	P04150	13/20	0.60

▸	PGR	P06401	4/20	0.60

▸	HIF1A	Q16665	3/20	0.60

▸	LMNA	P02545	3/20	0.60

▸	AR	P10275	2/20	0.60

▸	ALDH1A1	P00352	1/20	0.60

▸	MEN1	O00255	1/20	0.60

▸	KMT2A	Q03164	1/20	0.60

▸	CYP3A4	P08684	1/20	0.54

▸	MAPT	P10636	1/20	0.54

▸	HSD17B10	Q99714	1/20	0.54

▸	TDP1	Q9NUW8	1/20	0.54

▸	KDM4E	B2RXH2	1/20	0.54

▸	MAPK1	P28482	1/20	0.54

▸	ESR1	P03372	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21570003	0.93	NR3C1 (0.58)	NR3C1PGRHIF1ALMNAAR
SCHEMBL24591787	0.93	NR3C1 (0.58)	NR3C1PGRHIF1ALMNAAR
SCHEMBL21152658	0.93	NR3C1 (0.60)	NR3C1PGRHIF1ALMNAAR
SCHEMBL21152864	0.93	NR3C1 (0.60)	NR3C1PGRHIF1ALMNAAR
SCHEMBL21153641	0.93	NR3C1 (0.60)	NR3C1PGRHIF1ALMNAAR
SCHEMBL21152814	0.90	NR3C1 (0.56)	NR3C1PGRHIF1ALMNAAR
SCHEMBL21153614	0.89	NR3C1 (0.54)	NR3C1PGRHIF1ALMNAAR
SCHEMBL21153612	0.89	NR3C1 (0.54)	NR3C1PGRHIF1ALMNAAR
SCHEMBL21153731	0.89	NR3C1 (0.58)	NR3C1PGRHIF1ALMNAAR
SCHEMBL21153166	0.89	NR3C1 (0.66)	NR3C1PGRHIF1ALMNAAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019217591-A1	ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF	REGENERON PHARMACEUTICALS, INC. (US)	2019-11-14	—	—	WO	disclosed