Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 6/20 | 1.00 |
| ▸ | RORC | P51449 | 5/20 | 1.00 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 1/20 | 1.00 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 1.00 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.85 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.85 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.84 |
| ▸ | CRYAB | P02511 | 1/20 | 0.80 |
| ▸ | HMGCR | P04035 | 1/20 | 0.80 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.80 |
| ▸ | ITGAV | P06756 | 1/20 | 0.80 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.80 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.80 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.80 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.77 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.75 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cholesterol SCHEMBL21707472 | 1.00 | OSBP (1.00) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL21539517 | 1.00 | OSBP (1.00) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL22095727 | 1.00 | OSBP (1.00) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL21447271 | 1.00 | OSBP (1.00) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL23579652 | 1.00 | OSBP (1.00) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL21340667 | 1.00 | OSBP (1.00) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL23365796 | 1.00 | OSBP (1.00) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL21650234 | 1.00 | OSBP (1.00) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL23761109 | 1.00 | OSBP (1.00) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL21445079 | 1.00 | OSBP (1.00) | OSBPRORCOSBP2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 857687 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372210-B1 | — | — | None | — | — | US | claimed |
| JP-7025755-B2 | — | ファミリーイナダ株式会社 | 2022-02-25 | — | — | JP | claimed |
| US-9974748-B2 | Reduction of flake-like aggregation in nanoparticulate active agent compositions | ALKERMES PHARMA IRELAND LIMITED (IE) | 2018-05-22 | — | — | US | claimed |
| US-9974833-B2 | Methods of using compositions comprising variants and fusions of FGF19 polypeptides for modulating bile acid homeostasis in a subject having pregnancy intrahepatic cholestasis | NGM BIOPHARMACEUTICALS, INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-9974767-B2 | Statins in the treatment of muscular dystrophies and myopathies | UNIVERSITY OF WASHINGTON (US) | 2018-05-22 | — | — | US | claimed |
| US-9975983-B2 | Bio-reducible self-assembled liquid crystalline block copolymer for drug delivery | UNIVERSITY OF CONNECTICUT (US) | 2018-05-22 | — | — | US | claimed |
| US-9976168-B2 | Substance measurement method and measurement device employing electrochemical biosensor | ARKRAY, INC. (JP) | 2018-05-22 | — | — | US | claimed |
| US-20180133177-A1 | Treatment of NASH with Gemcabene | NEUROBO PHARMACEUTICALS, INC. | 2018-05-17 | — | — | US | claimed |
| US-20180133280-A1 | Compositions and Methods for Treating Diabetes, Hypertension and Hypercholesterolemia | IMAGINE PHARMA (US) | 2018-05-17 | — | — | US | claimed |
| US-20180135077-A1 | SERUM-FREE SUSPENSION SYSTEM FOR LENTIVIRAL PRODUCTION | Life Technologies Corporation | 2018-05-17 | — | — | US | claimed |
| US-3959484-A | Phenoxy carboxylic acid derivatives as anti-atheroslerosis agents | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-05-25 | — | — | US | claimed |
| US-3958034-A | Fractionated egg yolk product | CORNELL RESEARCH FOUNDATION, INC. (US) | 1976-05-18 | — | — | US | claimed |
| US-3957971-A | COSMETICS, LIPOSOMES, HUMECTANTS | LEVER BROTHERS COMPANY (US) | 1976-05-18 | — | — | US | claimed |
| US-3957976-A | FEEDING MALTITOL OR LACTITOL | KABUSHIKI-KAISHA HAYASHIBARA SEIBUTSUKAGAKU KENKYUJO (JA) | 1976-05-18 | — | — | US | claimed |
| US-3956484-A | Pyridylmethyl esters of N-(phenoxyalkanoyl)peptide derivatives for therepeutic use | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-05-11 | — | — | US | claimed |
| US-3954409-A | Method for determining serum cholesterol binding reserve and use in diagnosis | HSIA SUNG LAN | 1976-05-04 | — | — | US | claimed |
| US-3952096-A | Mixture of calcium carbonate and calcium-α-p-chlorophenoxyisobutyrate as an antihyperlipemic agent | BRISTOL-MYERS COMPANY (US) | 1976-04-20 | — | — | US | claimed |
| US-3950545-A | Baked product containing protein and vitamins and process for preparing same | THE QUAKER OATS COMPANY (US) | 1976-04-13 | — | — | US | claimed |
| US-3941892-A | FROZEN | GENERAL FOODS CORPORATION (US) | 1976-03-02 | — | — | US | claimed |
| US-3932657-A | Liposome encapsulation of chelating agents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES ENERGY RESEARCH AND DEVELOPMENT ADMINISTRATION (US) | 1976-01-13 | — | — | US | claimed |