Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157091 | 0.94 | KDM4E (0.43) | KDM4ESMN1; SMN2KMT2AALDH1A1GAA | |
| SCHEMBL2156914 | 0.91 | ALDH1A1 (0.39) | KDM4ESMN1; SMN2KMT2AALDH1A1HSD17B10 | |
| SCHEMBL2157504 | 0.91 | KDM4E (0.39) | KDM4ESMN1; SMN2KMT2AALDH1A1GAA | |
| SCHEMBL2156666 | 0.87 | KMT2A (0.39) | KDM4ESMN1; SMN2KMT2AALDH1A1GAA | |
| SCHEMBL2156282 | 0.79 | ALDH1A1 (0.37) | KDM4ESMN1; SMN2KMT2AALDH1A1GAA | |
| SCHEMBL2998711 | 0.79 | ALDH1A1 (0.42) | KDM4ESMN1; SMN2KMT2AALDH1A1HSD17B10 | |
| SCHEMBL2994395 | 0.79 | KDM4E (0.47) | KDM4ESMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL2156471 | 0.77 | KDM4E (0.36) | KDM4ESMN1; SMN2KMT2AALDH1A1GAA | |
| SCHEMBL2998829 | 0.77 | KMT2A (0.40) | KDM4ESMN1; SMN2KMT2AALDH1A1GAA | |
| SCHEMBL2156309 | 0.76 | ALDH1A1 (0.43) | KDM4EKMT2AALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973026-B2 | Thienopyrroles as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-07-05 | — | — | US | disclosed |
| US-20090105227-A1 | Thienopyrroles As Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105227-A1 | Thienopyrroles As Antiviral Agents | ZC3HAV1, HAVCR2, ZC3HAV1L | KDM4E 3275/4885SMN1; SMN2 4123/4885KMT2A 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.