SCHEMBL2157176

SCHEMBL2157176

O=c1ccn([C@@H]2O[C@]3(CO)CO[C@@H]2[C@H]3O)c(=O)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.49
SLC28A2 O43868 1/20 0.49
SLC29A1 Q99808 1/20 0.49
SLC28A3 Q9HAS3 1/20 0.49
P2RY6 Q15077 7/20 0.45
P2RY2 P41231 9/20 0.41
P2RY14 Q15391 1/20 0.41
P2RY4 P51582 3/20 0.39
ADORA3 P0DMS8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4078262 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2766878 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL14929468 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL13722079 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL13978164 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2157170 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2511160 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL13976549 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL5558240 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL1097185 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2341058-A2 Oligonucleotide Analogues Exiqon A/S (DK) 2011-07-06 EP disclosed