SCHEMBL5558240

SCHEMBL5558240

O=c1ccn([C@@H]2O[C@]3(CO)CO[C@H]2[C@H]3O)c(=O)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.49
SLC28A2 O43868 1/20 0.49
SLC29A1 Q99808 1/20 0.49
SLC28A3 Q9HAS3 1/20 0.49
P2RY6 Q15077 7/20 0.45
P2RY2 P41231 9/20 0.41
P2RY14 Q15391 1/20 0.41
P2RY4 P51582 3/20 0.39
ADORA3 P0DMS8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4078262 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2766878 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL14929468 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL13722079 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL13978164 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2157170 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2511160 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2157176 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL13976549 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL1097185 1.00 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7034133-B2 Locked Nucleoside Analogues is a biochemical conjugate of nucleotides; as an aptamer in specific binding of antibiotics, drugs, amino acids, peptides, enzymes, saccharides, polysaccharides; heat resistance EXIQON A/S (DK) 2006-04-25 US claimed
EP-1178999-B1 L-RIBO-LNA ANALOGUES SANTARIS PHARMA AS (DK) 2007-03-14 EP disclosed
US-7053207-B2 L-ribo-LNA analogues EXIQON A/S (DK) 2006-05-30 US disclosed
US-20030087230-A1 L-Ribo-LNA analogues SANTARIS PHARMA A/S (DK) 2003-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087230-A1 L-Ribo-LNA analogues RNGTT, NCL, RNASEL SLC28A1 188/4885SLC28A2 152/4885SLC29A1 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.