Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.44 |
| ▸ | ITGAL | P20701 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2504920 | 0.80 | ITGB2 (0.44) | ITGB2ICAM1ITGALMTNR1AADRB1 | |
| SCHEMBL8306057 | 0.80 | MTNR1A (0.45) | ITGB2ICAM1ITGALMTNR1AADRB1 | |
| Hydrochloric Acid SCHEMBL2461132 | 0.78 | MTNR1A (0.44) | ITGB2ICAM1ITGALMTNR1AADRB1 | |
| SCHEMBL21571866 | 0.76 | MTNR1A (0.42) | ITGB2ICAM1ITGALMTNR1AADRB1 | |
| SCHEMBL15650620 | 0.76 | MTNR1A (0.45) | ITGB2ICAM1ITGALMTNR1A | |
| SCHEMBL16703460 | 0.74 | MRGPRX1 (0.52) | MTNR1AKDM4EMRGPRX1LMNASMN1; SMN2 | |
| SCHEMBL6114083 | 0.73 | MRGPRX1 (0.45) | ITGB2ICAM1ITGALMTNR1AKDM4E | |
| SCHEMBL2961606 | 0.73 | MTNR1A (0.57) | MTNR1AKDM4EMRGPRX1ABCB1FLT1 | |
| SCHEMBL24312061 | 0.72 | ITGB2 (0.50) | ITGB2ICAM1ITGALMTNR1AADRB1 | |
| SCHEMBL22421809 | 0.72 | MTNR1A (0.42) | MTNR1AMRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3151669-B1 | USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2020-10-28 | — | — | EP | disclosed |
| US-10479793-B2 | Imidazopyridazine compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479793-B2 | Imidazopyridazine compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses | TYK2, IL2, JAK3 | ITGB2 1154/4885ICAM1 2833/4885ITGAL 1982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.