Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21572143 | 0.97 | RAB9A (0.37) | RAB9ANPC1ALDH1A1L3MBTL1POLB | |
| SCHEMBL21572131 | 0.90 | HPGD (0.33) | RAB9ANPC1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL21572154 | 0.89 | RAB9A (0.36) | RAB9ANPC1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL21572148 | 0.89 | HPGD (0.34) | RAB9ANPC1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL21572152 | 0.88 | RAB9A (0.37) | RAB9ANPC1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL21572145 | 0.88 | RAB9A (0.34) | RAB9ANPC1ALDH1A1L3MBTL1POLB | |
| SCHEMBL20084271 | 0.87 | RAB9A (0.37) | RAB9ANPC1ALDH1A1L3MBTL1POLB | |
| SCHEMBL20085114 | 0.85 | RAB9A (0.39) | RAB9ANPC1ALDH1A1L3MBTL1POLB | |
| SCHEMBL20084333 | 0.85 | RAB9A (0.39) | RAB9ANPC1ALDH1A1L3MBTL1POLB | |
| SCHEMBL21572142 | 0.84 | RAB9A (0.33) | RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10479780-B2 | Aminopyrazole derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2019-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479780-B2 | Aminopyrazole derivatives | SRC, GRK2, GRK3 | RAB9A 2990/4885NPC1 4566/4885ALDH1A1 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.