Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553795 | 0.92 | APP (0.41) | APPDYRK1APTGER4 | |
| SCHEMBL17544215 | 0.92 | APP (0.41) | APPDYRK1APTGER4 | |
| SCHEMBL30401661 | 0.91 | DYRK1A (0.48) | APPDYRK1APTGER4 | |
| SCHEMBL17544093 | 0.91 | DYRK1A (0.48) | APPDYRK1APTGER4 | |
| Hydrochloric Acid SCHEMBL17544187 | 0.91 | APP (0.40) | APPDYRK1APTGER4 | |
| SCHEMBL17544482 | 0.90 | MAPT (0.41) | APPPDE10ADYRK1AHPGDS | |
| SCHEMBL24465551 | 0.89 | APP (0.39) | APPDYRK1APTGER4 | |
| SCHEMBL17543901 | 0.80 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL30402527 | 0.79 | HDAC6 (0.48) | APP | |
| SCHEMBL17544324 | 0.79 | HDAC6 (0.48) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10479802-B2 | Probes for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2019-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479802-B2 | Probes for imaging huntingtin protein | HTT, HYPK, FABP7 | APP 229/4885PDE10A 3443/4885IKBKB 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.