Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568619 | 0.80 | ADRB2 (0.59) | ADRB2CHRM3ADRB1 | |
| SCHEMBL18897362 | 0.80 | ADRB2 (0.59) | ADRB2CHRM3ADRB1 | |
| SCHEMBL21573581 | 0.73 | ADRB2 (0.55) | ADRB2CHRM3ADRB1 | |
| SCHEMBL21568555 | 0.72 | ADRB2 (0.53) | ADRB2CHRM3ADRB1 | |
| SCHEMBL21568557 | 0.72 | ADRB2 (0.53) | ADRB2CHRM3ADRB1 | |
| SCHEMBL21568643 | 0.71 | ADRB2 (0.51) | ADRB2CHRM3ADRB1 | |
| SCHEMBL21568641 | 0.71 | ADRB2 (0.51) | ADRB2CHRM3ADRB1 | |
| SCHEMBL18259878 | 0.71 | ADRB2 (0.79) | ADRB2CHRM3 | |
| SCHEMBL18259876 | 0.71 | ADRB2 (0.79) | ADRB2CHRM3 | |
| SCHEMBL28338759 | 0.71 | ADRB2 (0.79) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303333-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2019-11-20 | — | — | EP | disclosed |