Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 17/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4895143 | 0.92 | ADRB2 (0.66) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL4890724 | 0.88 | ADRB2 (0.61) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL4628320 | 0.86 | ADRB2 (0.55) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL17513858 | 0.86 | ADRB2 (0.55) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL25906764 | 0.86 | ADRB2 (0.55) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL25265416 | 0.84 | ADRB2 (0.53) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL25196431 | 0.84 | ADRB2 (0.53) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL2004900 | 0.84 | ADRB2 (0.77) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL244647 | 0.84 | ADRB2 (0.77) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL18259967 | 0.84 | ADRB2 (0.44) | ADRB2ADRB1DRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303333-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2019-11-20 | — | — | EP | disclosed |