Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26356049 | 0.93 | KDM4E (0.42) | KDM4EATML3MBTL1NPSR1PLA2G2A | |
| SCHEMBL22257891 | 0.93 | KDM4E (0.42) | KDM4EATML3MBTL1NPSR1PLA2G2A | |
| SCHEMBL21573684 | 0.93 | L3MBTL1 (0.42) | KDM4EATML3MBTL1NPSR1PLA2G2A | |
| SCHEMBL22240756 | 0.93 | KDM4E (0.42) | KDM4EATML3MBTL1NPSR1PLA2G2A | |
| SCHEMBL23947795 | 0.92 | KDM4E (0.41) | KDM4EATML3MBTL1PLA2G2APLA2G4A | |
| SCHEMBL24264430 | 0.92 | KDM4E (0.41) | KDM4EATML3MBTL1PLA2G2APLA2G4A | |
| SCHEMBL23947525 | 0.92 | KDM4E (0.41) | KDM4EATML3MBTL1PLA2G2APLA2G4A | |
| SCHEMBL23947797 | 0.92 | KDM4E (0.41) | KDM4EATML3MBTL1PLA2G2APLA2G4A | |
| SCHEMBL24264029 | 0.92 | KDM4E (0.41) | KDM4EATML3MBTL1PLA2G2APLA2G4A | |
| SCHEMBL23947527 | 0.92 | KDM4E (0.41) | KDM4EATML3MBTL1PLA2G2APLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569603-A1 | POLYCYCLIC COMPOUND, AND ORGANIC ELECTROLUMINESCENCE ELEMENT COMPRISING THE POLYCYCLIC COMPOUND | Idemitsu Kosan Co., Ltd. (JP) | 2019-11-20 | — | — | EP | disclosed |