Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 8/20 | 0.54 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936775 | 1.00 | TYMP (0.54) | TYMPP2RY12ADORA1PRMT6ADORA2A | |
| SCHEMBL21652355 | 1.00 | TYMP (0.54) | TYMPP2RY12ADORA1PRMT6ADORA2A | |
| SCHEMBL17861061 | 1.00 | TYMP (0.54) | TYMPP2RY12ADORA1PRMT6ADORA2A | |
| SCHEMBL21158665 | 1.00 | TYMP (0.54) | TYMPP2RY12ADORA1PRMT6ADORA2A | |
| SCHEMBL19509810 | 1.00 | TYMP (0.54) | TYMPP2RY12ADORA1PRMT6ADORA2A | |
| SCHEMBL13010052 | 0.94 | TYMP (0.51) | TYMPP2RY12PRMT6 | |
| SCHEMBL6900160 | 0.92 | TYMP (0.56) | TYMPP2RY12ADORA1ADORA2AADORA2B | |
| SCHEMBL30200670 | 0.92 | TYMP (0.56) | TYMPP2RY12ADORA1ADORA2AADORA2B | |
| SCHEMBL6834984 | 0.92 | TYMP (0.56) | TYMPP2RY12ADORA1ADORA2AADORA2B | |
| SCHEMBL1040958 | 0.92 | TYMP (0.56) | TYMPP2RY12ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569711-A1 | LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS | Dicerna Pharmaceuticals, Inc. (US) | 2019-11-20 | — | — | EP | disclosed |