SCHEMBL13010052

SCHEMBL13010052

C#CCOCCCCOC1C(O)C(COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)OC1n1cnc2c(NC(=O)c3ccccc3)ncnc21

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TYMP P19971 7/20 0.51
P2RY12 Q9H244 1/20 0.42
GAPDH P04406 2/20 0.41
PRMT6 Q96LA8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13010051 0.95 TYMP (0.51) TYMPP2RY12
SCHEMBL13010058 0.94 TYMP (0.46) TYMPP2RY12GAPDHPRMT6
SCHEMBL21158665 0.94 TYMP (0.54) TYMPP2RY12PRMT6
SCHEMBL17861061 0.94 TYMP (0.54) TYMPP2RY12PRMT6
SCHEMBL19509810 0.94 TYMP (0.54) TYMPP2RY12PRMT6
SCHEMBL29936775 0.94 TYMP (0.54) TYMPP2RY12PRMT6
SCHEMBL21574271 0.94 TYMP (0.54) TYMPP2RY12PRMT6
SCHEMBL21652355 0.94 TYMP (0.54) TYMPP2RY12PRMT6
SCHEMBL6894664 0.91 TYMP (0.54) TYMPP2RY12GAPDH
SCHEMBL6898807 0.91 TYMP (0.55) TYMPP2RY12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100317714-A1 COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS SUZHOU RIBO LIFE SCIENCE CO., LTD (CN) 2010-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317714-A1 COMPLEX MOLECULE INTERFERING THE EXPRESSION OF TARGET GENES AND ITS PREPARING METHODS DCLRE1B, RNASE1, AGO2 TYMP 1836/4885P2RY12 4613/4885GAPDH 2050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.