Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16633028 | 0.89 | RORC (0.60) | RORC | |
| SCHEMBL16632673 | 0.88 | RORC (0.65) | RORC | |
| SCHEMBL16639519 | 0.84 | RORC (0.57) | RORC | |
| SCHEMBL16632809 | 0.82 | RORC (0.76) | RORC | |
| SCHEMBL16632970 | 0.81 | RORC (0.78) | RORC | |
| SCHEMBL16632939 | 0.80 | RORC (0.81) | RORC | |
| SCHEMBL16633457 | 0.80 | RORC (0.69) | RORC | |
| SCHEMBL16639565 | 0.80 | RORC (0.61) | RORC | |
| SCHEMBL16632858 | 0.80 | RORC (0.57) | RORC | |
| SCHEMBL16639483 | 0.80 | RORC (0.73) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057951-B1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2019-11-20 | — | — | EP | disclosed |