SCHEMBL215748

SCHEMBL215748

CC(C)CCCC1(C)OCCCCO1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 12/20 0.31
LMNA P02545 1/20 0.31
PDPK1 O15530 1/20 0.31
PHLPP1 O60346 1/20 0.31
ILK Q13418 1/20 0.31
CETP P11597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215615 0.91 LMNA (0.33) AKT1LMNAPDPK1PHLPP1ILK
SCHEMBL10596394 0.87
SCHEMBL15821979 0.84 LMNA (0.48) LMNA
SCHEMBL15822117 0.84 LMNA (0.48) LMNA
SCHEMBL15821982 0.84 LMNA (0.48) LMNA
SCHEMBL15822118 0.84 LMNA (0.48) LMNA
SCHEMBL11399707 0.84 LMNA (0.48) LMNA
SCHEMBL17269118 0.83 LMNA (0.36) LMNA
SCHEMBL17269266 0.83 LMNA (0.36) LMNA
SCHEMBL12126630 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2514812-B1 Fragrance compositions and compounds GIVAUDAN SA (CH) 2018-10-03 EP disclosed
CN-101641431-B Fragrance compositions and compounds QUEST INT SERV BV 2013-02-20 CN disclosed
EP-2514812-A2 Fragrance compositions and compounds Givaudan Nederland Services B.V. (NL) 2012-10-24 EP disclosed
EP-2514812-A2 Fragrance compositions and compounds Givaudan Nederland Services B.V. (NL) 2012-10-24 EP disclosed
US-8088725-B2 Fragrance compositions and compounds GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2012-01-03 US disclosed
US-8088725-B2 Fragrance compositions and compounds GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2012-01-03 US disclosed
US-8088725-B2 Fragrance compositions and compounds GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2012-01-03 US disclosed
US-20100132249-A1 Fragrance Compositions and Compounds GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2010-06-03 US disclosed
US-20100132249-A1 Fragrance Compositions and Compounds GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2010-06-03 US disclosed
US-20100132249-A1 Fragrance Compositions and Compounds GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2010-06-03 US disclosed
CN-101641431-A Flavor compositions and compound QUEST INT SERV BV NL 2010-02-03 CN disclosed
EP-2118249-A2 FRAGRANCE COMPOSITIONS AND COMPOUNDS Givaudan Nederland Services B.V. (NL) 2009-11-18 EP disclosed
WO-2008092678-A2 FRAGRANCE COMPOSITIONS AND COMPOUNDS GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2008-08-07 WO disclosed
WO-2008092678-A2 FRAGRANCE COMPOSITIONS AND COMPOUNDS GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2008-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100132249-A1 Fragrance Compositions and Compounds H1-0, H1-10, H1-5 AKT1 2988/4885LMNA 2425/4885PDPK1 3054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.