Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 19/20 | 0.52 |
| ▸ | CHIA | Q9BZP6 | 19/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.46 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21574965 | 0.88 | CHIT1 (0.48) | CHIT1CHIAKCNH2CHI3L1 | |
| SCHEMBL17838864 | 0.87 | CHIT1 (0.60) | CHIT1CHIAKCNH2CHI3L1 | |
| SCHEMBL21575102 | 0.86 | CHIT1 (0.58) | CHIT1CHIAKCNH2 | |
| SCHEMBL16825724 | 0.84 | CHIT1 (0.71) | CHIT1CHIAKCNH2CHI3L1 | |
| SCHEMBL21574973 | 0.83 | CHIT1 (0.49) | CHIT1CHIAKCNH2CHI3L1 | |
| SCHEMBL17838848 | 0.82 | CHIT1 (0.49) | CHIT1CHIAKCNH2CHI3L1 | |
| SCHEMBL16825876 | 0.82 | CHIA (0.70) | CHIT1CHIAKCNH2 | |
| SCHEMBL16825836 | 0.82 | CHIT1 (0.73) | CHIT1CHIAKCNH2CHI3L1 | |
| SCHEMBL16826354 | 0.80 | CHIA (0.59) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838829 | 0.79 | CHIT1 (0.53) | CHIT1CHIAKCNH2CHI3L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233832-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-11-20 | — | — | EP | disclosed |