Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 20/20 | 0.58 |
| ▸ | CHIA | Q9BZP6 | 20/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 16/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21575038 | 0.90 | CHIT1 (0.55) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838834 | 0.87 | CHIT1 (0.75) | CHIT1CHIAKCNH2 | |
| SCHEMBL16825739 | 0.86 | CHIT1 (0.63) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838838 | 0.85 | CHIT1 (0.61) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838828 | 0.84 | CHIT1 (0.62) | CHIT1CHIAKCNH2 | |
| SCHEMBL21574955 | 0.84 | CHIT1 (0.57) | CHIT1CHIAKCNH2 | |
| SCHEMBL17854055 | 0.83 | CHIT1 (0.62) | CHIT1CHIAKCNH2 | |
| SCHEMBL16826109 | 0.83 | CHIT1 (0.72) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838871 | 0.83 | CHIT1 (0.75) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838886 | 0.83 | CHIT1 (0.61) | CHIT1CHIAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233832-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-11-20 | — | — | EP | disclosed |