SCHEMBL2157526

SCHEMBL2157526

CCN(CCS(=O)(=O)O)c1ccc(N)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
L3MBTL1 Q9Y468 4/20 0.58
TSHR P16473 3/20 0.58
MAPK1 P28482 2/20 0.58
PSMD14 O00487 1/20 0.58
CYP3A4 P08684 1/20 0.58
RECQL P46063 1/20 0.58
GFER P55789 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
MEN1 O00255 2/20 0.46
HPGD P15428 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP2C19 P33261 2/20 0.46
HSP90AA1 P07900 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2D6 P10635 1/20 0.41
ESRRG P62508 1/20 0.41
CNR2 P34972 1/20 0.40
MAPT P10636 2/20 0.39
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15894604 0.90 ALDH1A1 (0.55) ALDH1A1L3MBTL1TSHRMAPK1PSMD14
SCHEMBL11152893 0.89 ALDH1A1 (0.53) ALDH1A1L3MBTL1TSHRMAPK1PSMD14
SCHEMBL9631136 0.85 CNR2 (0.48) ALDH1A1L3MBTL1TSHRMAPK1MEN1
Sulfuric Acid SCHEMBL1304807 0.84 ALDH1A1 (0.76) ALDH1A1L3MBTL1TSHRMAPK1PSMD14
Sulfuric Acid SCHEMBL20570213 0.83 ALDH1A1 (0.58) ALDH1A1L3MBTL1TSHRMAPK1PSMD14
Sulfuric Acid SCHEMBL1143794 0.83 ALDH1A1 (0.58) ALDH1A1L3MBTL1TSHRMAPK1PSMD14
SCHEMBL6850621 0.83 TSHR (0.47) ALDH1A1L3MBTL1TSHRGFERMEN1
Sulfuric Acid SCHEMBL11787283 0.82 ALDH1A1 (0.73) ALDH1A1L3MBTL1TSHRMAPK1PSMD14
Sulfuric Acid SCHEMBL3892651 0.82 ALDH1A1 (0.56) ALDH1A1L3MBTL1TSHRMAPK1PSMD14
SCHEMBL11036559 0.82 ALDH1A1 (0.45) ALDH1A1L3MBTL1MEN1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459900-B2 Process for dyeing of keratinic fibres with 2,4-diamino-1,3-dimethoxybenzene in an acid medium and composition using this process OREAL (FR) 2002-08-28 EP claimed
US-5900028-A Oxidation dye composition for keratin fibres comprising 2-amino-3-hydroxypyridine and a P-phenylenediamine or P-aminophenol oxidation base, and dyeing process L 'OREAL (FR) 1999-05-04 US claimed
US-5735909-A Compositions and processes for the oxidation dyeing of keratin fibres with an oxidation base, a meta-aminophenol coupler, and a 6-hydroxyindoline coupler L'OREAL (FR) 1998-04-07 US claimed
EP-0766958-B1 Oxidation dyeing composition for keratinous fibers comprising 2-amino-3-hydroxypyridine and an oxidation base and dyeing process OREAL (FR) 1997-11-19 EP claimed
EP-0605320-B1 Dye composition for keratinic fibres based on paraphenylenediamine, metaphenylenediamines and benzimidazol derivates, and the dyeing process using same OREAL (FR) 1997-04-09 EP claimed
EP-0728465-B1 Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition OREAL (FR) 1997-03-19 EP claimed
US-5578087-A Dyeing compositions for keratinous fibres based on para-phenylene-diamines, meta-phenylenediamine and benzimidazole derivatives, and dyeing process employing them L'OREAL (FR) 1996-11-26 US claimed
EP-0506549-B1 Dyeing composition for keratinous fibers containing oxidation dye precursors and hydroxybenzofurans as couplers and dyeing process making use of such a composition OREAL (FR) 1995-10-18 EP claimed
EP-0446132-B1 Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions OREAL (FR) 1994-09-14 EP claimed
EP-0459900-B1 Process for dyeing of keratinic fibres with 2,4-diamino-1,3-dimethoxybenzene in an acid medium and composition using this process OREAL (FR) 1994-01-05 EP claimed
EP-0416962-B1 KERATINOUS FIBERS DYEING PROCESS WITH INDOLE DYES AND OXIDATION DYE PRECURSORS AND DYEING AGENTS L'OREAL (FR) 1993-09-22 EP claimed
US-RE34300-E Hair dye L'OREAL (FR) 1993-07-06 US claimed
US-5203875-A Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance L'OREAL (FR) 1993-04-20 US claimed
US-5073174-A Hair, two stage, deep warm colors L'OREAL (FR) 1991-12-17 US claimed
EP-0295474-B1 CHLOROMETAPHENYLENEDIAMINES, THEIR USE AS COUPLING AGENTS IN OXYDATION COLOURING OF KERATINIC FIBRES, COLOURITY COMPOSITIONS FOR HAIR CONTAINING THESE COMPOUNDS AND COLOURING PROCESS USING THESE COMPOSITIONS L'OREAL (FR) 1991-07-17 EP claimed
US-4865619-A Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler L'OREAL (FR) 1989-09-12 US claimed
US-4865618-A New chloro-meta-phenylenediamines, their use as couplers in the oxidation dyeing of keratinous fibres, dyeing compositions for hair containing these compounds and dyeing process using the said L'OREAL (FR) 1989-09-12 US claimed
US-4692166-A OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE L'OREAL (FR) 1987-09-08 US claimed
WO-2022191865-A1 HAIR COLORANT ASSESSMENT, SELECTION AND FORMULATION SYSTEM Innovative Beauty LLC (US) 2022-09-15 WO disclosed
US-4066457-A P-PHENYLENEDIAMINE DERIVATIVES GAF CORPORATION (US) 1978-01-03 US disclosed