Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23502901 | 0.92 | GAA (0.36) | GAAMAPTNR1H4KMT2ASMN1; SMN2 | |
| SCHEMBL23809545 | 0.91 | GAA (0.35) | GAAMAPTNR1H4KMT2ASMN1; SMN2 | |
| SCHEMBL24877693 | 0.90 | GAA (0.38) | GAAMAPTNR1H4KMT2ASMN1; SMN2 | |
| SCHEMBL23106281 | 0.90 | GAA (0.39) | GAAMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21308177 | 0.88 | GAA (0.39) | GAAMAPTNR1H4KMT2ASMN1; SMN2 | |
| SCHEMBL23879737 | 0.86 | GAA (0.35) | GAAMAPTNR1H4KMT2ASMN1; SMN2 | |
| SCHEMBL23879734 | 0.85 | SMN1; SMN2 (0.39) | GAAMAPTNR1H4KMT2ASMN1; SMN2 | |
| SCHEMBL23502894 | 0.83 | GAA (0.37) | GAAMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21538137 | 0.82 | KMT2A (0.39) | GAAMAPTNR1H4KMT2ASMN1; SMN2 | |
| SCHEMBL24518132 | 0.82 | TP53BP1 (0.38) | GAAMAPTKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295437-A1 | SILICON CONTAINING DETECTABLE COMPOUNDS | Singular Genomics Systems, Inc. | 2023-09-21 | — | — | US | disclosed |
| US-11697736-B2 | Silicon containing detectable compounds | Singular Genomics Systems, Inc. (US) | 2023-07-11 | — | — | US | disclosed |
| US-20220119779-A1 | MODIFIED PYROCOCCUS POLYMERASES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-04-21 | — | — | US | disclosed |
| US-20190352508-A1 | SILICON CONTAINING DETECTABLE COMPOUNDS | FIRST-CITIZENS BANK & TRUST COMPANY | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697736-B2 | Silicon containing detectable compounds | AS3MT, SCLY, NASP | GAA 251/4885MAPT 4045/4885NR1H4 3518/4885 |
| US-20230295437-A1 | SILICON CONTAINING DETECTABLE COMPOUNDS | AS3MT, SCLY, NASP | GAA 251/4885MAPT 4045/4885NR1H4 3518/4885 |
| US-20190352508-A1 | SILICON CONTAINING DETECTABLE COMPOUNDS | AS3MT, SCLY, NASP | GAA 251/4885MAPT 4045/4885NR1H4 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.