Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23240005 | 0.87 | CYP1A2 (0.38) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL20033519 | 0.85 | HTR2A (0.32) | HTR2AHTR2CHTR2BPDE2A | |
| SCHEMBL21387111 | 0.83 | — | — | |
| SCHEMBL11891645 | 0.81 | HTR2A (0.39) | HTR2AHTR2CHTR2BPTGS1PTGS2 | |
| SCHEMBL21526942 | 0.80 | HTR2A (0.35) | HTR2AHTR2CHTR2BPDE2A | |
| SCHEMBL21226545 | 0.76 | PTGS1 (0.34) | HTR2AHTR2CHTR2BPTGS1PTGS2 | |
| SCHEMBL26865534 | 0.74 | HTR2A (0.35) | HTR2AHTR2CHTR2BPTGS1PTGS2 | |
| SCHEMBL20150824 | 0.74 | PTGS1 (0.30) | PTGS1PTGS2 | |
| SCHEMBL11891650 | 0.74 | HTR2A (0.37) | HTR2AHTR2CHTR2BPTGS1PTGS2 | |
| SCHEMBL11891651 | 0.74 | HTR2A (0.37) | HTR2AHTR2CHTR2BPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306251-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2022-04-19 | — | — | US | disclosed |
| US-20190352564-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-11-21 | — | — | US | disclosed |