Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21226545 | 0.84 | PTGS1 (0.34) | PTGS1PTGS2 | |
| SCHEMBL11891645 | 0.78 | HTR2A (0.39) | PTGS1PTGS2 | |
| SCHEMBL21577568 | 0.74 | HTR2A (0.37) | PTGS1PTGS2 | |
| SCHEMBL22622686 | 0.73 | DRD2 (0.33) | — | |
| SCHEMBL20033519 | 0.72 | HTR2A (0.32) | — | |
| SCHEMBL11891650 | 0.71 | HTR2A (0.37) | PTGS1PTGS2 | |
| SCHEMBL11891651 | 0.71 | HTR2A (0.37) | PTGS1PTGS2 | |
| SCHEMBL11891647 | 0.69 | HTR2A (0.36) | PTGS2 | |
| SCHEMBL29209831 | 0.68 | AR (0.37) | — | |
| SCHEMBL19445483 | 0.67 | ABCB1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134696-A1 | Aminobenzisoxazole Compounds as Agonists of Alpha7-Nicotinic Acetylcholine Receptors | FORUM PHARMACEUTICALS, INC. | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134696-A1 | Aminobenzisoxazole Compounds as Agonists of Alpha7-Nicotinic Acetylcholine Receptors | CHRNA7, CHRNA5, CHRNA2 | PTGS1 4339/4885PTGS2 4247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.