SCHEMBL21578032

SCHEMBL21578032

Cc1ccccc1C(=O)c1ccc2c(c1)c1ccccc1n2C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.64
HTT P42858 2/20 0.64
KDM4E B2RXH2 4/20 0.64
CNR2 P34972 1/20 0.48
HPGD P15428 4/20 0.47
GPR3 P46089 1/20 0.46
RORC P51449 1/20 0.46
NPY5R Q15761 1/20 0.45
MAPT P10636 3/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
HSD17B10 Q99714 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAPK13 O15264 1/20 0.44
MAPK12 P53778 1/20 0.44
MAPK11 Q15759 1/20 0.44
MAPK14 Q16539 1/20 0.44
ALKBH5 Q6P6C2 1/20 0.44
FTO Q9C0B1 1/20 0.44
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31145039 0.90 ALDH1A1 (0.63) ALDH1A1HTTKDM4ECNR2HPGD
SCHEMBL626556 0.90 ALDH1A1 (0.63) ALDH1A1HTTKDM4ECNR2HPGD
SCHEMBL14124824 0.86 KDM4E (0.73) ALDH1A1HTTKDM4ECNR2HPGD
SCHEMBL22828642 0.85 CNR2 (0.65) ALDH1A1HTTCNR2HPGDNPC1
SCHEMBL16774030 0.85 HPGD (0.68) ALDH1A1HTTCNR2HPGDRORC
SCHEMBL3417160 0.85 KDM4E (0.57) ALDH1A1HTTKDM4ECNR2HPGD
SCHEMBL30832750 0.85 KDM4E (0.57) ALDH1A1HTTKDM4ECNR2HPGD
SCHEMBL29370263 0.85 KDM4E (0.57) ALDH1A1HTTKDM4ECNR2HPGD
SCHEMBL15906317 0.83 MAPT (0.60) ALDH1A1HTTKDM4EMAPTKMT2A
SCHEMBL626557 0.83 ALDH1A1 (0.55) ALDH1A1HTTKDM4ECNR2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11225605-B2 Polymerizable liquid crystal compound, method for producing polymerizable liquid crystal compound, polymerizable liquid crystal composition, optically anisotropic film, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2022-01-18 US disclosed
US-20190352567-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, METHOD FOR PRODUCING POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, OPTICALLY ANISOTROPIC FILM, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2019-11-21 US disclosed