Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.38 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21579349 | 0.91 | ALDH1A1 (0.39) | ALDH1A1GAAL3MBTL1GRM5SORT1 | |
| SCHEMBL20177031 | 0.86 | GRM5 (0.49) | ALDH1A1GAAL3MBTL1GRM5SORT1 | |
| SCHEMBL21579345 | 0.84 | CCNA2 (0.48) | ALDH1A1GAAL3MBTL1GRM5SORT1 | |
| SCHEMBL21579432 | 0.75 | CCNA2 (0.47) | GRM5NPC1RAB9ABRAFMAP3K5 | |
| SCHEMBL15877592 | 0.73 | GRM5 (0.48) | ALDH1A1GAAL3MBTL1GRM5SORT1 | |
| SCHEMBL21579348 | 0.70 | NPC1 (0.62) | GAAL3MBTL1GRM5SORT1NPC1 | |
| SCHEMBL21579386 | 0.70 | NPC1 (0.48) | GRM5SORT1NPC1RAB9ABRAF | |
| SCHEMBL16594252 | 0.69 | GRM5 (0.53) | GRM5SORT1RIOK2BRAF | |
| SCHEMBL30050714 | 0.69 | GRM5 (0.53) | GRM5SORT1RIOK2BRAF | |
| SCHEMBL20016544 | 0.69 | DEGS1 (0.50) | ALDH1A1GAAL3MBTL1GRM5SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190352276-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | JOINT STOCK COMPANY "BIOCAD" (RU) | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190352276-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | BTK, ABL1, CNKSR1 | ALDH1A1 3977/4885GAA 2173/4885L3MBTL1 593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.