Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23686674 | 0.86 | PPARA (0.42) | SMN1; SMN2HPGDPPARALMNAPPARD | |
| SCHEMBL23686573 | 0.85 | PPARA (0.39) | HPGDPPARALMNAEPHX2NR1H4 | |
| SCHEMBL21580050 | 0.76 | HPGD (0.42) | KDM4EALDH1A1RAB9AHPGDPPARA | |
| SCHEMBL21580095 | 0.76 | NAMPT (0.49) | KDM4EALDH1A1HTTSMN1; SMN2HPGD | |
| SCHEMBL21580145 | 0.76 | PPARG (0.41) | KDM4EALDH1A1RAB9AHPGDPPARA | |
| SCHEMBL21580094 | 0.69 | SCN3A (0.49) | KDM4ENPC1ALDH1A1HTTRAB9A | |
| SCHEMBL21580024 | 0.68 | MAOB (0.49) | — | |
| SCHEMBL21580062 | 0.67 | NAMPT (0.47) | HTTSMN1; SMN2LMNAHDAC1 | |
| SCHEMBL6556153 | 0.66 | PPARA (0.63) | ALDH1A1HTTSMN1; SMN2HPGDPPARA | |
| SCHEMBL21580115 | 0.65 | SCN3A (0.50) | KDM4ELMNAMAPTL3MBTL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019218024-A1 | PAIN TREATING COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2019-11-21 | — | — | WO | disclosed |