Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31089761 | 1.00 | SCN9A (0.42) | SCN9ARIOK2P2RX3KDRBRAF | |
| SCHEMBL21611234 | 0.89 | SCN9A (0.42) | SCN9ACTSSCTSKADORA3AAK1 | |
| SCHEMBL21611225 | 0.88 | RAF1 (0.42) | SCN9AKDRBRAFAAK1 | |
| SCHEMBL21611230 | 0.86 | AAK1 (0.39) | SCN9AKDRCTSSCTSKAAK1 | |
| SCHEMBL31089887 | 0.84 | SCN9A (0.47) | SCN9ARIOK2P2RX3CTSSCTSK | |
| SCHEMBL21581664 | 0.84 | SCN9A (0.47) | SCN9ARIOK2P2RX3CTSSCTSK | |
| SCHEMBL31089812 | 0.84 | SCN9A (0.48) | SCN9ACTSSCTSKADORA3ABCB1 | |
| SCHEMBL31089865 | 0.83 | HDAC4 (0.41) | SCN9ACTSSCTSKAAK1MMP13 | |
| SCHEMBL21581662 | 0.83 | HDAC4 (0.41) | SCN9ACTSSCTSKAAK1MMP13 | |
| SCHEMBL9923870 | 0.82 | HDAC4 (0.41) | SCN9ACTSSCTSKHDAC8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019222816-A1 | SUBSTITUTED-PYRIDINYL COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2019-11-28 | — | — | WO | disclosed |