Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21581617 | 0.89 | SCN9A (0.39) | SCN9AKDM4EALDH1A1HPGDCTSK | |
| SCHEMBL21581673 | 0.88 | SCN9A (0.37) | L3MBTL1GFERHSD17B10SCN9AKDM4E | |
| SCHEMBL21581680 | 0.83 | SCN9A (0.36) | HSD17B10SCN9ACACNA1BCTSKKLK5 | |
| SCHEMBL31089836 | 0.82 | SCN9A (0.49) | L3MBTL1GFERHSD17B10SCN9AKDM4E | |
| SCHEMBL21581626 | 0.78 | KDM4E (0.40) | L3MBTL1HSD17B10KDM4EALDH1A1MTNR1B | |
| SCHEMBL21581621 | 0.74 | SCN9A (0.47) | SCN9AKDM4EALDH1A1HPGDCACNA1B | |
| SCHEMBL21581600 | 0.74 | SCN9A (0.55) | SCN9AKDM4EALDH1A1HPGDCACNA1B | |
| SCHEMBL21581607 | 0.73 | SCN9A (0.50) | SCN9AKDM4EALDH1A1HPGDCACNA1B | |
| SCHEMBL31089812 | 0.71 | SCN9A (0.48) | SCN9ACTSKMAPTABCB1 | |
| SCHEMBL31089903 | 0.71 | SCN9A (0.48) | HSD17B10SCN9AKDM4EALDH1A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019222816-A1 | SUBSTITUTED-PYRIDINYL COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2019-11-28 | — | — | WO | disclosed |