Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21581609 | 0.88 | L3MBTL1 (0.40) | SCN9AABCB1L3MBTL1GFERHSD17B10 | |
| SCHEMBL21581617 | 0.87 | SCN9A (0.39) | SCN9AKLK5KDM4EALDH1A1HPGD | |
| SCHEMBL21581680 | 0.84 | SCN9A (0.36) | SCN9AABCB1HSD17B10ITGB1ITGA4 | |
| SCHEMBL31089812 | 0.83 | SCN9A (0.48) | SCN9AABCB1CTSSCTSKNPC1 | |
| SCHEMBL21581594 | 0.80 | PFKFB3 (0.36) | ITGB1ITGA4ALDH1A1NPC1MAPT | |
| SCHEMBL21581607 | 0.78 | SCN9A (0.50) | SCN9AABCB1KDM4EALDH1A1HPGD | |
| SCHEMBL21581618 | 0.77 | SCN9A (0.48) | SCN9AABCB1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL31089903 | 0.77 | SCN9A (0.48) | SCN9AABCB1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL21611230 | 0.73 | AAK1 (0.39) | SCN9AABCB1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL21581608 | 0.73 | NPC1 (0.42) | SCN9AL3MBTL1GFERHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019222816-A1 | SUBSTITUTED-PYRIDINYL COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2019-11-28 | — | — | WO | disclosed |