Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.96 |
| ▸ | DNM1 | Q05193 | 10/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29706404 | 1.00 | LMNA (0.96) | LMNADNM1HTTHSP90AA1RAD52 | |
| Bromide SCHEMBL1494723 | 1.00 | LMNA (0.96) | LMNADNM1HTTHSP90AA1RAD52 | |
| Bromide SCHEMBL28429574 | 1.00 | LMNA (0.96) | LMNADNM1HTTHSP90AA1RAD52 | |
| Bromide SCHEMBL28430194 | 1.00 | LMNA (0.96) | LMNADNM1HTTHSP90AA1RAD52 | |
| Bromide SCHEMBL29712384 | 1.00 | LMNA (0.96) | LMNADNM1HTTHSP90AA1RAD52 | |
| SCHEMBL13388580 | 0.98 | LMNA (1.00) | LMNADNM1HTTHSP90AA1RAD52 | |
| SCHEMBL1123475 | 0.98 | LMNA (1.00) | LMNADNM1HTTHSP90AA1RAD52 | |
| SCHEMBL31255930 | 0.98 | LMNA (1.00) | LMNADNM1HTTHSP90AA1RAD52 | |
| SCHEMBL2710518 | 0.98 | LMNA (1.00) | LMNADNM1HTTHSP90AA1RAD52 | |
| SCHEMBL10608031 | 0.98 | LMNA (1.00) | LMNADNM1HTTHSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119708953-A | Long-acting low-surface-energy coating with high recoating performance, and preparation method and application thereof | 四川大学 | 2025-03-28 | — | — | CN | claimed |
| CN-116262623-A | Metal modified hierarchical porous high-silicon Y molecular sieve and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2023-06-16 | — | — | CN | claimed |
| CN-111303637-A | Preparation method of medical organic silicon rubber composition | 孟令芝 | 2020-06-19 | — | — | CN | claimed |
| CN-111286203-A | Medical organic silicon rubber composition | 孟令芝 | 2020-06-16 | — | — | CN | claimed |
| US-6323260-B1 | AMINOHYDROCARBONSILOXANE MOIETY COMPRISING BOTH SILICON AND NITROGEN. | BAYER INC. (CA) | 2001-11-27 | — | — | US | claimed |
| EP-1131379-A1 | PROCESS FOR HYDROPHOBICIZING PARTICLES, AND THEIR USE IN DISPERSIONS | Bayer Inc. (CA) | 2001-09-12 | — | — | EP | claimed |
| WO-2000031178-A1 | PROCESS FOR HYDROPHOBICIZING PARTICLES, AND THEIR USE IN DISPERSIONS | BAYER INC. (CA) | 2000-06-02 | — | — | WO | claimed |
| CN-119708953-A | Long-acting low-surface-energy coating with high recoating performance, and preparation method and application thereof | 四川大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-116262623-A | Metal modified hierarchical porous high-silicon Y molecular sieve and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2023-06-16 | — | — | CN | disclosed |
| EP-2880102-B1 | PARTICULATE METAL OXIDE PARTICLES COMPRISING A METAL OXIDE CORE AND A COATING LAYER COMPRISING AN INORGANIC MATERIAL, A SILANE COUPLING AGENT AND/OR A HYDROPHOBIZING AGENT. | CRODA INT PLC (GB) | 2022-06-29 | — | — | EP | disclosed |
| US-10869826-B2 | Particulate metal oxide particles comprising a metal oxide core and a coating layer comprising an inorganic material, a silane coupling agent and/or a hydrophobizing agent | CRODA INTERNATIONAL PLC | 2020-12-22 | — | — | US | disclosed |
| CN-111303637-A | Preparation method of medical organic silicon rubber composition | 孟令芝 | 2020-06-19 | — | — | CN | disclosed |
| CN-111286203-A | Medical organic silicon rubber composition | 孟令芝 | 2020-06-16 | — | — | CN | disclosed |
| US-6407153-B1 | Silica-containing rubber compositions | BAYER INC. (CA) | 2002-06-18 | — | — | US | disclosed |
| EP-1208145-A2 | PROCESS FOR PREPARATION OF RUBBER SILICA MASTERBATCHES BASED ON THE USE OF POLYMER LATICES | Bayer Inc. (CA) | 2002-05-29 | — | — | EP | disclosed |
| US-6323260-B1 | AMINOHYDROCARBONSILOXANE MOIETY COMPRISING BOTH SILICON AND NITROGEN. | BAYER INC. (CA) | 2001-11-27 | — | — | US | disclosed |
| US-20010009948-A1 | Elastomeric butyl compounds with improved chemical bonding between the butyl elastomer and the filler | BAYER INC. (CA) | 2001-07-26 | — | — | US | disclosed |
| WO-2001010946-A2 | PROCESS FOR PREPARATION OF RUBBER SILICA MASTERBATCHES BASED ON THE USE OF POLYMER LATICES | BAYER INC. (CA) | 2001-02-15 | — | — | WO | disclosed |
| EP-0983317-A1 | PROCESS FOR HYDROPHOBICIZING PARTICLES, AND THEIR USE AS FILLERS IN POLYMER MASTERBATCHES | Bayer Inc. (CA) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998053004-A1 | PROCESS FOR HYDROPHOBICIZING PARTICLES, AND THEIR USE AS FILLERS IN POLYMER MASTERBATCHES | BAYER INC. (CA) | 1998-11-26 | — | — | WO | disclosed |