Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 11/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21581702 | 0.93 | OPRD1 (0.46) | OPRD1OPRM1OPRK1PTPN2PTPN1 | |
| SCHEMBL21581715 | 0.84 | OPRD1 (0.44) | OPRD1OPRM1OPRK1CCKBR | |
| SCHEMBL25627199 | 0.79 | OPRD1 (0.46) | OPRD1OPRM1OPRK1PTPN2PTPN1 | |
| SCHEMBL21581711 | 0.78 | OPRD1 (0.45) | OPRD1OPRM1OPRK1CCKBR | |
| SCHEMBL26454272 | 0.76 | NPY4R (0.61) | — | |
| SCHEMBL15839930 | 0.75 | OPRD1 (0.54) | OPRD1OPRM1OPRK1 | |
| SCHEMBL17082298 | 0.72 | OPRD1 (0.58) | OPRD1OPRM1OPRK1 | |
| SCHEMBL17074564 | 0.72 | OPRD1 (0.65) | OPRD1OPRM1OPRK1 | |
| SCHEMBL22435589 | 0.71 | OPRD1 (0.52) | OPRD1CCKBR | |
| SCHEMBL28911173 | 0.71 | OPRD1 (0.57) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019222805-A1 | NEW SYNTHETIC METHODS USING NATIVE CHEMICAL LIGATION IN FLOW | THE UNIVERSITY OF SYDNEY (AU) | 2019-11-28 | — | — | WO | disclosed |