⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21582317 | 0.87 | GAA (0.32) | — | |
| SCHEMBL12558322 | 0.82 | — | — | |
| SCHEMBL8603802 | 0.75 | — | — | |
| SCHEMBL5846168 | 0.74 | TSHR (0.40) | — | |
| SCHEMBL347199 | 0.73 | — | — | |
| SCHEMBL595648 | 0.71 | — | — | |
| SCHEMBL11469410 | 0.68 | — | — | |
| SCHEMBL8868873 | 0.68 | LMNA (0.32) | — | |
| SCHEMBL6525946 | 0.67 | TP53 (0.32) | — | |
| SCHEMBL16043323 | 0.65 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775532-A | Preparation method and application of low-viscosity low-volatility hyperbranched epoxy resin | 上海信斯帝克新材料有限公司 | 2025-04-08 | — | — | CN | claimed |
| US-12344597-B2 | Alkoxy-substituted pyridinyl derivatives as LPA1 receptor antagonists and their use in the treatment of fibrosis | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-07-01 | — | — | US | disclosed |
| CN-119775532-A | Preparation method and application of low-viscosity low-volatility hyperbranched epoxy resin | 上海信斯帝克新材料有限公司 | 2025-04-08 | — | — | CN | disclosed |
| EP-3802517-B1 | ALKOXY-SUBSTITUTED PYRIDINYL DERIVATIVES AS LPA1 RECEPTOR ANTAGONISTS AND THEIR USE IN THE TREATMENT OF FIBROSIS | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-12-21 | — | — | EP | disclosed |
| US-20210246116-A1 | ALKOXY-SUBSTITUTED PYRIDINYL DERIVATIVES AS LPA1 RECEPTOR ANTAGONISTS AND THEIR USE IN THE TREATMENT OF FIBROSIS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-08-12 | — | — | US | disclosed |
| EP-3802517-A1 | ALKOXY-SUBSTITUTED PYRIDINYL DERIVATIVES AS LPA1 RECEPTOR ANTAGONISTS AND THEIR USE IN THE TREATMENT OF FIBROSIS | Idorsia Pharmaceuticals Ltd (CH) | 2021-04-14 | — | — | EP | disclosed |
| WO-2019234115-A1 | ALKOXY-SUBSTITUTED PYRIDINYL DERIVATIVES AS LPA1 RECEPTOR ANTAGONISTS AND THEIR USE IN THE TREATMENT OF FIBROSIS | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-12-12 | — | — | WO | disclosed |